Research

My key research area is on the abuse of psychotropic substances, addiction treatment and harm-reduction prevention.  My research interests include studying the long-term effects of ketum (Mitragyna speciosa) use in ketum users, identifying methadone treatment barriers, assessing risky injection and sexual behaviours of amphetamine-type-stimulants (amphetamine/methamphetamine) users, determining treatment needs of female-drug users, as well as evaluating the effectiveness of evidence-based harm reduction programs such as methadone therapy and needle-exchange program.  I also conduct research to monitor the current trends and health and social issues related to the drug abuse situation in the country.  My research basically involves out-of-treatment heroin, ATS, ketamine, poly-drug users and people who used New Psychoactive Substances (NPS).  I am also proactively involved in University-Community engagement programs targeting communities plagued with substance abuse problems.  My research aims to determine the social, health and economic impact of drug use on the quality-of-life of drug users.

Current Research Project:

• Risky sexual and criminal behaviours of amphetamine type stimulant (ATS) users in Penang
• Barriers to treatment compliance among patients in Methadone Maintenance Treatment (MMT) Program in Malaysia
• Opiate treatment barriers and risky sexual behaviours of female drug users (FDUs) in Malaysia
• Risky behaviours and psychological problems in pil kuda (ATS) users in Kelantan
• Behavioural characteristics and cognitive evaluation in ketum (Mitragyna speciosa) users in Malaysia

People

Current PhD student (as main supervisor)

• Nadiah Mohd Saref
• Norazlin Mohd Saref

Current Masters students (as main supervisor)

• Charles George Gajim
• Harinderan A/L Krishnan
• Normazaini Mohd Noor
• Ruzmayuddin Mamat

Publications

SELECTED PUBLICATIONS (FROM 2010)

1. Leong Bin Abdullah M.F.I, Singh, D., Vicknasingam, B.K. 2018. Case report of recreational Lysergic-Aciddiethylamide (LSD) use In Malaysia. ASEAN Journal of Psychiatry, 19(1), 21-23.
2. Singh, D., Narayanan, S., Müller, C.P., Swogger, M.T., Rahim, A.A., Leong Bin Abdullah M.F.I., Vicknasingam, B.K. (2018) Severity of kratom (Mitragyna speciosa Korth.) psychological withdrawal symptoms. J Psychoactive Drugs. 2018 Aug 28:1-6. doi: 10.1080/02791072.2018.1511879. [Epub ahead of print]
3. Vicknasingam, B., Narayanan, S., Singh, D., Chawarski, M. (2018) Decriminalization of drug use. Curr Opin Psychiatry. 2018 May 8. doi: 10.1097/YCO.0000000000000429. [Epub ahead of print]
4. Singh, D., Murugaiyah, V., Hamid, S.B.S., Kasinather, V., Chan, M.S.A., Ho, E.T.W., Grundmann, O., Chear, N.J.Y., Mansor, S.M. (2018) Assessment of gonadotropins and testosterone hormone levels in regular Mitragyna speciosa (Korth.) users. J Ethnopharmacol., 221, 30-36
5. Singh, D., Narayanan, S., Vicknasingam, B.K., Prozialeck, W.C., Ramanathan, S., Zainal, H., Harun, S.N. (2018) Severity of Pain and Sleep Problems during Kratom (Mitragyna speciosa Korth.) Cessation among regular kratom users. J Psychoactive Drugs., 20, 1.
6. Singh, D., Müller, C.P., Murugaiyah, V., Hamid, S.B.S., Vicknasingam, B.K., Avery, B., Chear, N.J.Y., Mansor, S.M. (2018) Evaluating the hematological and clinical-chemistry parameters of kratom (Mitragyna speciosa) users in Malaysia. J Ethnopharmacol., 214, 197.
7. Hassan, Z., Bosch, O.G., Singh, D., Narayanan, S., Kasinather, B.V., Seifritz, E., Kornhuber, J., Quednow, B.B., Müller, C.P. (2017) Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs. Front Psychiatry, 8, 152.
8. Singh, D., Narayanan, S., Vicknasingam, B., Corazza, O., Santacroce, R., Roman-Urrestarazu, A. (2017) Changing trends in the use of kratom (Mitragyna speciosa) in Southeast Asia. Hum Psychopharmacol., doi: 10.1002/hup.2582. 
9. Singh, D., Narayanan, S., Vicknasingam, B. (2016) Traditional and non-traditional uses of Mitragynine (Kratom): A survey of the literature. Brain Res Bull., 126 (Pt 1), 41-46.
10. Suppiah, B., Vicknasingam, B., Singh, D., Narayanan, S. (2016) Erectile dysfunction among people who use ketamine and poly-drugs. J Psychoactive Drugs, 48 (2), 86-92.
11. Cinosi, E., Martinotti, G., Singh, D., Demetrovics, Z.,  Roman-Urrestarazu, A., Bersani, F.S., Vicknasingam, B., Piazzon, G., Li, J.H., Yu, W.J., Kapitány-Fövény, M., Farkas, J., Di Giannantonio, M., Corazza, O. (2015) Following “the roots” of Kratom (Mitragyna speciosa): The evolution of an enhancer from a traditional use to increase work and productivity in South-East Asia to a recreational psychoactive drug in Western Countries. BioMed Res Int., Article ID 968786.
12. Vicknasingam, B., Narayanan, S., Singh, D. (2015) The rise of groin injection among opiate drug users in Malaysia. International Journal of Prevention and Treatment of Substance Use Disorders, 1 (3), 142-152.
13. Vicknasingam, B., Dazali., M.N., Singh, D., Schottenfeld, R.S., Chawarski, M.C. (2015) Buprenorphine/naloxone treatment practices in Malaysia: Results of national survey of physician and patients. Drug Alcohol Depend., 152, 164-169.
14. Singh, D., Müller, C.P., Vicknasingam B.K., Mansor, S.M. (2015) Social-functioning of Kratom (Mitragyna speciosa) users in Malaysia. J Psychoactive Drugs, 47 (2), 125-131.
15. Singh, D., Müller C.P., Vicknasingam B.K. (2014) Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users. Drug Alcohol Depend., 139, 132-137.
16. Singh, D., Chawarski, M.C., Schottenfeld, R., Vicknasingam, B. (2013) Substance abuse and HIV situation in Malaysia. J Food Drug Anal., 21 (4), S46-51.

Selected Reports (from 2010)

1. Most-at-risk children in central Kuala Lumpur; What do they think and know about risk? Report for UNICEF Malaysia (2013) Assisted principal investigator in data collection and data analysis.
2. A study of most-at-risk women in urban Kuala Lumpur. Report for UNICEF Malaysia (2013) Assisted principal investigator in data collection and data analysis.
3. Prepared report for ‘Kertas Cadangan Bagi Membangunkan Model Holistik Terbaik Program Pendidikan Inklusif Untuk Malaysia’. Report prepared for Ministry of Education (2013).
4. The informal use of Kratom among the local masses in the northern states of Malaysia (2010) Assisted principal investigator in data collection and drafting manuscript for publication.

Published Abstract

1. Cinosi, E., Simonato, P., Singh, D., Bersani, F.S., Piazzon, G., Lupi, M., Marini, S., Kapitány-Fövény, M., Farkas, J., Demetrovics, Z., Roman-Urrestarazu, A., Vicknasingam, B., Li, J.H., Yu, W.J., Santacroce, R., Acciavatti, T., Martinotti, G., Di Giannantonio, M., Corazza, O. (2016) A comprehensive overview on Kratom. European Psychiatry, 33, S354-S355.